Maximum score: 98%
Minimum score: 45%
FINAL SCALE:
284-256 = A
255-225 = B
224-197 = C
196-152 = D
| Average score: 75% Maximum score: 98% Minimum score: 45% FINAL SCALE: 284-256 = A 255-225 = B 224-197 = C 196-152 = D |
|
Questions numbered 1 through 25 count 2 points each (50 points).
| B | 1. | (1) | The probability that infection with Hepatitis A virus will produce a chronic infection. | |
| (2) | The probability that infection with Hepatitis C virus will produce a chronic infection. | |||
| A | 2. | (1) | The correlation between infection by EBV and the specific cancer referred to as Burkitt's lymphoma. | |
| (2) | The correlation between infection by HIV and the specific cancer referred to as Burkitt's lymphoma. | |||
| A | 3. | (1) | The probability of acquiring coccidioidomycosis in the southwestern United States. | |
| (2) | The probability of acquiring paracoccidioidomycosis in the southwestern United States. | |||
| B | 4. | (1) | The frequency of recurrence of acute disease by Varicella-Zoster virus. | |
| (2) | The frequency of recurrence of acute disease by Herpes Simplex virus. | |||
| B | 5. | (1) | The presence of a lipid bilayer envelope surrounding the Picornavirus nucleocapsid. | |
| (2) | The presence of a lipid bilayer envelope surrounding the Paramyxovirus nucleocapsid. | |||
| A | 6. | (1) | The probability of corneal scarring and eventual blindness as a result of trachoma. | |
| (2) | The probability of corneal scarring and eventual blindness as a result of inclusion conjunctivitis. | |||
| A | 7. | (1) | Transmission of West Nile Encephalitis virus from birds to mosquitos to humans. | |
| (2) | Transmission of Yellow Fever virus from birds to mosquitos to humans. | |||
| A | 8. | (1) | The probability that the lesions resulting from smallpox will lead to scarring. | |
| (2) | The probability that the lesions resulting from chickenpox will lead to scarring. | |||
| C | 9. | (1) | The importance of a viremic phase in the disease caused by the Measles virus. | |
| (2) | The importance of a viremic phase in the disease caused by the Mumps virus. | |||
| A | 10. | (1) | The occurrence of Negri bodies following infection by Rhabdovirus. | |
| (2) | The occurrence of Negri bodies following infection by Rhinovirus. | |||
| A | 11. | (1) | The probability that a rash produced by infection with Rickettsia prowazekii will spread in a centrifugal manner. | |
| (2) | The probability that a rash produced by infection with Rickettsia rickettsii will spread in a centrifugal manner. | |||
| B | 12. | (1) | The occurrence of lower respiratory tract infections by RSV in adults. | |
| (2) | The occurrence of lower respiratory tract infections by RSV in infants. | |||
| A | 13. | (1) | The optimal temperature for the growth of Coxsackie viruses. | |
| (2) | The optimal temperature for the growth of Rhinoviruses. | |||
| C | 14. | (1) | The need for an RNA-dependent RNA polymerase during the replicative cycle of negative-stranded RNA viruses. | |
| (2) | The need for an RNA-dependent RNA polymerase during the replicative cycle of positive-stranded RNA viruses. | |||
| A | 15. | (1) | The affinity of the HIV gp120 protein for the T-cell receptor CD4. | |
| (2) | The affinity of the HIV gp120 protein for the T-cell receptor CD8. | |||
| B | 16. | (1) | The role of a non-human animal reservoir in the transmission of epidemic relapsing fever. | |
| (2) | The role of a non-human animal reservoir in the transmission of endemic relapsing fever. | |||
| A | 17. | (1) | The importance of the humoral immune response in preventing disease caused by Corynebacterium diphtheriae. | |
| (2) | The importance of the humoral immune response in preventing disease caused by Mycobacterium tuberculosis. | |||
| B | 18. | (1) | Transmission of polio via the respiratory route. | |
| (2) | Transmission of polio via the fecal-oral route. | |||
| C | 19. | (1) | The occurrence of a rash following infection by Rickettsia rickettsii. | |
| (2) | The occurrence of a rash following infection by Rubellavirus. | |||
| B | 20. | (1) | The time between epidemics of influenza that result from the process of antigenic drift. | |
| (2) | The time between epidemics of influenza that result from the process of antigenic shift. | |||
| B | 21. | (1) | The number of different serotypes of the Mumps virus. | |
| (2) | The number of different serotypes of the Poliovirus. | |||
| A | 22. | (1) | Administration of the Salk vaccine via the parenteral route. | |
| (2) | Administration of the Sabin vaccine via the parenteral route. | |||
| C | 23. | (1) | The ability of Influenza A virus to undergo the process of antigenic drift. | |
| (2) | The ability of HIV to undergo the process of antigenic drift. | |||
| C | 24. | (1) | The role of fleas in the transmission of Q fever to humans. | |
| (2) | The role of fleas in the transmission of spotted fever to humans. | |||
| A | 25. | (1) | The observation that the symmetry associated with the Rhabdovirus nucleocapsid is helical. | |
| (2) | The observation that the symmetry associated with the Rhabdovirus nucleocapsid is icosahedral. |
Questions 26-30: Indicate the one most important MODE OF TRANSMISSION listed on the right for each of the DISEASES or VIRUSES listed on the left. Each lettered choice may be used once, more than once or not at all. | |||||
| B | 26. | Hepatitis A virus | A. | Respiratory | |
| C | 27. | Typhus | B. | Fecal-Oral | |
| A | 28. | Histoplasmosis | C. | Arthropod/Insect-borne | |
| D | 29. | Hepatitis C virus | D. | Blood-borne | |
| C | 30. | Chikungungya virus | E. | All of the above | |
| F. | None of the above | ||||
Questions 31-33: Indicate the one most important HOST DEFENSE MECHANISM listed on the right for each of the AGENTS listed on the left. Each lettered choice may be used once, more than once or not at all. | |||||
| C | 31. | Measles virus | A. | Cell-mediated immunity | |
| C | 32. | Rubella virus | B. | Antitoxin antibodies | |
| B | 33. | Corynebacterium diphtheriae | C. | Neutralizing antibodies | |
| D. | Opsonization/phagocytosis | ||||
| E. | Anatomical barriers | ||||
| F. | None | ||||
Questions 34-38: Indicate the one most important CONTROL METHOD listed on the right for each of the DISEASE AGENTS listed on the left. Each lettered choice may be used once, more than once or not at all. | |||||
| D | 34. | Rickettsia rickettsii | A. | Vaccination | |
| A | 35. | Polio virus | B. | Avoiding human contacts | |
| D | 36. | Yellow Fever virus | C. | Sanitation/Safe water supply | |
| B | 37. | RSV | D. | Vector control | |
| B | 38. | Chlamydia trachomatis | E. | None of the above | |
| A. | Blastomyces dermatitidis | B. | Chlamydia trachomatis |
| C. | Corynebacterium diphtheriae | D. | Epstein-Barr virus |
| E. | Hepatitis A virus | F. | Hepatitis B virus |
| G. | Herpes Simplex virus | H. | HIV |
| I. | Influenza virus | J. | Measles virus |
| K. | Mumps virus | L. | Mycobacterium tuberculosis |
| M. | Respiratory Syncytial virus | N. | Rhabdovirus |
| O. | Rickettsia prowazekii | P. | Rickettsia rickettsii |
| R. | Varicella-Zoster virus | S. | Yellow Fever virus |
| D | 39. | i) patient is a 14-year old female, ii) patient complains of fever, fatigue, malaise and a sore throat, iii) laboratory findings include an elevated white blood cell count and atypical B-cells. |
| P | 40. | i) patient has returned from a field trip in the woods, ii) symptoms include fever, headache, and a rash that began on the arms, iii) indirect fluorescent antibody test is positive. |
| B | 41. | i) patient is a 23-year old graduate student who recently met “the girl of his dreams”, ii) patient now complains of a urethral discharge and pain on urination, iii) treatment with tetracycline is curative. |
| L | 42. | i) patient is a middle-aged male, ii) patient reports having a prolonged and productive cough, iii) a skin test demonstrates a strong cell-mediated immune reaction. |
| I | 43. | i) patient is a middle aged female, ii) symptoms occurred suddenly and include fever, headache, sore throat, malaise and muscle aches, iii) tissue culture of nasopharyngeal material is capable of adsorbing red blood cells. |
| M | 44. | i) patient is a 7-week old infant girl, ii) patient is dehydrated and wheezing with respiratory distress, iii) a rapid test kit reveals a negative-stranded RNA virus. |
| G | 45. | i) patient is a college student preparing for their most difficult final exam, ii) patient experiences an extremely sore spot just inside the lips, iii) examination of the sore area reveals a small ulcer in the oral cavity. |
| F | 46. | i) patient recently required a blood transfusion, ii) symptoms include elevated serum alanine transaminase levels, iii) ELISA test positive for Australian antigen. |
| EXTRA CREDIT POINTS | |
| (2 points) Name the virus that has a cone-shaped nucleocapsid. HIV | |
| (2 points) Name the virus that has a bullet-shape. Rhabdovirus | |